Theme
Proteomics in Disease Biology
Proteins are the prime targets of drug development of any disease innate or pathogenic in origin. When
the proteins are mutation prone and rapidly evolving, proteomics can help us to track the complex
molecular changes that shape up the course of the disease and thus ease our quest of finding new drug
targets.
Continuous threat of pandemic outbreaks of infectious diseases (dengue, COVID19, etc.) puts us on high
alert and coerces us to use a multi-omics approach to gain more information about the proteome of the
viruses and the host pathogen interactions. This helps us to identify the rate limiting pathways in the virus
life cycle and potential targets to throttle it.
Further, the innate disease conditions where multiple factors give rise to similar phenotypes, for instance
– neurodegenerative disorders or diabetes, the results from a single layer of data are not sufficient to give
a mechanistic insight. Therefore using a coordinated set of multiple omics data is the key to reveal novel
information. Come join us to know more on how Omics tools and techniques can be used to decipher
disease biology.