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Theme

Proteomics in Disease Biology

Proteins are the prime targets of drug development of any disease innate or pathogenic in origin. When the proteins are mutation prone and rapidly evolving, proteomics can help us to track the complex molecular changes that shape up the course of the disease and thus ease our quest of finding new drug targets.

Continuous threat of pandemic outbreaks of infectious diseases (dengue, COVID19, etc.) puts us on high alert and coerces us to use a multi-omics approach to gain more information about the proteome of the viruses and the host pathogen interactions. This helps us to identify the rate limiting pathways in the virus life cycle and potential targets to throttle it.

Further, the innate disease conditions where multiple factors give rise to similar phenotypes, for instance – neurodegenerative disorders or diabetes, the results from a single layer of data are not sufficient to give a mechanistic insight. Therefore using a coordinated set of multiple omics data is the key to reveal novel information. Come join us to know more on how Omics tools and techniques can be used to decipher disease biology.

Current Perspective of Proteomics

  • Proteomic Techniques
  • Targeted Proteomics
  • Integrative Omics: Proteomics, Genomics and Metabolomics
  • Application in Diagnostics

Proteomics in Disease Biology

  • Proteinopathies & Neurodegenerative Disorders
  • Cancer, Cardiac and Metabolic Disorders
  • Clinical and pharmaceutical proteomics

Disordered proteins and proteomics

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Proteomics in Food, Agriculture and Biotechnology

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